Vaccines in practice

SOLD OUT!!

Wednesday 22nd May 2019
Doors Open 18:30 | Event 19:00 - 22:00
Cafe The Crown
Gedempte Zuiderdiep 2, 9711 HG 

What in vitro means:how to predict if a vaccine works (without killing animals)

Despite still being a controversial topic, vaccination is among the most important advances in history. Since their invention, vaccines have been continuously improved and their production perfectioned. Now, the last frontier in vaccinology is to develop methods to test the safety and efficacy of a vaccine without having to rely on in vivo (live animals) systems. This is done using cell-based (or in vitro) methods that can mimic, at least partly, the reaction of the immune system to a vaccine.

Aurora Signorazzi

PhD student

University of Groningen

Development of a therapeutic vaccine for cervical cancer

Human papilloma virus (HPV) infection is associated with over 99% cases of cervical cancer. Despite the availability of highly effective prophylactic HPV vaccines, still many women will develop (pre)malignant cervical lesions. We have developed a therapeutic vaccine, rSFVeE6,7 that demonstrated robust anti-tumor responses with complete regression of tumors in mice. With these promising findings, we now performed a phase I clinical trial.

 

Amrita Singh

PhD student

University of Groningen

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